Genetic Diseases: Cystic Fibrosis and Huntington's Disease

TLDR; The video discusses cystic fibrosis and Huntington's disease, their genetic causes, Punnett squares, and biological significances.

⚗️ Cystic Fibrosis

Cystic fibrosis is a significant genetic disease due to being the most common genetic disease in Europe.

It is caused by a recessive allele of the CFTR gene located on chromosome number seven, affecting the chloride ion channel's shape.

This results in the secretion of sticky mucus, which can clog bronchioles and airways.

Using a Punnett square, it's possible to determine the chances of inheriting cystic fibrosis from carrier parents.

The Punnett square shows three possible genotypes: big C big C (normal), big C little C (carrier), and little C little C (cystic fibrosis).

⚕️ Huntington's Disease

Huntington's disease is a genetic disease caused by a dominant allele from the HTT gene located on chromosome number 4, resulting in harmful effects such as brain degeneration and changes in behavior.

Using a Punnett square, it's possible to determine the chances of inheriting Huntington's disease from carrier parents.

The Punnett square shows that anyone with a dominant allele will show the disease, while those without it will not show the disease.

It's important to understand the genetic causes of these diseases and their impact on body systems for a comprehensive understanding of genetics.

🧬 Biological Significance

Understanding genetics and its link to proteins, body systems, and membrane transport is crucial in comprehending the significance of genetic diseases like cystic fibrosis and Huntington's disease.

The link between genetics, protein function, and biological systems provides insights into the impact of genetic diseases on the human body.

The video emphasizes the importance of comprehending the big picture of genetics and its implications for human health and well-being.